金钱草组方对犬草酸钙尿结石形成的影响

doi:10.11843/j.issn.0366-6964.2015.10.021

Abstract

Abstract:

The experiment was designed to preliminary study on the effect of Jinqiancao compound potion to the formation of calcium oxalate stones in the urine of canine.Twelve healthy male Canis Lupus familiaris were randomly divided into 3 groups，which were the control group，the model group and the treatment group.The dogs in control group were fed with basal diet.The dogs in model group and treatment group were fed with basal diet plus glycol，ammonium chloride，calcium carbonate and vitamin D.Once 80% of the microscope view appeared calcium oxalate crystals in the urine of the experimental dogs，the Jinqiancao compound potion was orally administrated to the dogs of treatment group.During the experiment，the urine index(including the content of microalbumin，the enzymatic activity of N-acetyl-β-D-Glucosaminidase and γ-glutamyltransferase) and the serum index(including the content of creatinine，blood urea nitrogen，uric acid and malondialdehyde，the enzymatic activity of lactate dehydrogenase and superoxide dismutase) were detected.Results were as follows：compared with model group，by treating Jinqiancao compound potion，the treatment group appeared lower activity of N-acetyl-β-D-Glucosaminidase，lower activity of γ-glutamyltransferase，lower concent of serum uric acid，lower malondialdehyde，lower activity of lactate dehydrogenase and higher activity of serum superoxide dismutase than that of modle group.Our study demonstrates that Jinqiancao compound can effectively reduce the damage to renal during the formation of calcium oxalate calculus，improve the enzyme activity of blood antioxidant.In other words，kidney cells were effectively repaired to ensure the function of kidney by the Jinqiancao compound，which to prevent the formation of calcium oxalate calculus in the urine of canine.

CLC Number:

S856.59

HE Ding-ling，HU Fang-fang，SU Yong-kang，QIU Xian-shuai，XIAO Xi-yu，PAN Jia-qiang. Effect of Jinqiancao Compound Potion on the Formation of Calcium Oxalate Stones in the Urine of Canine[J]. ACTA VETERINARIA ET ZOOTECHNICA SINICA, 2015, 46(10): 1867-1874.

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Effect of Jinqiancao Compound Potion on the Formation of Calcium Oxalate Stones in the Urine of Canine

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